Rhythm Tech
Rhythm Tech
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Would a Mucomyst treatment affect a person's cardiac activity?
I was sitting in with a telemetry technician and we were watching a guy's ECG. I can't remember what his baseline rhythm was, but I know it wasn't a normal sinus rhythm. Every time he received a Mucomyst treatment, he would start having runs of V-tach. The tele tech would inform the RN each time it would occur, and the RN stated he was getting his Mucomyst treatment again.
The doctor came in and said that Mucomyst would not be the cause of his runs of V-tach. I did look up the medication and did not read any drug facts about cardiac side effects, so I'm just curious if it was merely coincidence? Perhaps anxiety driven response? Or was there a connection that may be rare?
I'm a nursing student so I'm just curious about these little things that pop up from time to time.
Three possible things come to mind:
IV Mucomyst (acetylcysteine) can cause anaphylactoid reactions, the released histamine can cause a drop in blood pressure with reflex tachycardia.
Tachycardia (without explanation) occurs 1 to 4 percent of the time with IV mucomyst.
http://www.merck.com/mmpe/lexicomp/acetylcysteine.html
Another possibility might be a drug interaction with the drugs the patient may already be taking. We know that acetylcysteine aids in the neutralization of the toxic metabolite of acetaminophen, but it also might aid in the inactivation of other drugs. For many drug interactions they are not discovered until someone notices a problem.